2,4-dimethylthiophan 1,1-dioxide
2,4-Dimethylsulfolane
CAS: 1003-78-7
Molecular Formula: C6H12O2S
2,4-dimethylthiophan 1,1-dioxide - Names and Identifiers
2,4-dimethylthiophan 1,1-dioxide - Physico-chemical Properties
| Molecular Formula | C6H12O2S |
| Molar Mass | 148.22 |
| Density | 1.136g/mLat 25°C(lit.) |
| Melting Point | −3°C(lit.) |
| Boling Point | 281°C(lit.) |
| Flash Point | 294°F |
| Vapor Presure | 0.00688mmHg at 25°C |
| Appearance | liquid |
| Refractive Index | n20/D 1.473(lit.) |
2,4-dimethylthiophan 1,1-dioxide - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | XN0525000 |
2,4-dimethylthiophan 1,1-dioxide - Introduction
2,4-Dimethyl sulfolane, chemical formula C6H12O2S, often abbreviated as DMS, is an organic sulfur compound. The following is a description of some properties, uses, methods and safety information about 2,4-dimethyl sulfolane:
Nature:
1. Appearance: 2,4-dimethyl sulfolane is a colorless to light yellow liquid.
2. Density: The density of 2,4-dimethylsulfolane is 1.06 g/mL.
3. Melting point: The melting point of 2,4-dimethyl sulfolane is 18-20°C.
4. Boiling Point: The boiling point of 2,4-dimethylsulfolane is 138°C.
5. Storage conditions: 2,4-dimethyl sulfolane should be stored in a cool, dry, well-ventilated place, away from open flames and high temperatures.
Use:
1. Solvent: 2,4-Dimethyl Sulfolane is a polar solvent that can be used to dissolve organic and inorganic substances.
2. reaction intermediate: 2,4-dimethyl sulfolane can be used as a reaction intermediate in the process of organic synthesis, commonly used in the synthesis of catalysts or promoters.
3. Drug synthesis: 2,4-Dimethylsulfolane is widely used in the field of drug synthesis, such as the synthesis of antibiotics, hormones and other drugs.
Preparation Method:
The preparation methods of 2,4-dimethyl sulfolane are mainly as follows:
1. sulfuric acid method: methyl cyclobutane is oxidized to generate 2,4-dimethyl cyclobutanone, and then reacted with sulfuric acid to generate 2,4-dimethyl sulfolane.
2. ammonium chloride method: the reaction of methyl cyclobutene and ammonium chloride to generate 2-methyl cyclobutanone, and then react with sodium bisulfite to generate 2,4-dimethyl sulfolane.
Safety Information:
1. 2,4-Dimethyl sulfolane is irritating and may cause irritation and burns when in contact with skin and eyes. Direct contact should be avoided.
2. in use or operation, should wear appropriate protective gloves, glasses and protective clothing.
3. If inhaled or ingested by mistake, seek medical attention immediately.
Nature:
1. Appearance: 2,4-dimethyl sulfolane is a colorless to light yellow liquid.
2. Density: The density of 2,4-dimethylsulfolane is 1.06 g/mL.
3. Melting point: The melting point of 2,4-dimethyl sulfolane is 18-20°C.
4. Boiling Point: The boiling point of 2,4-dimethylsulfolane is 138°C.
5. Storage conditions: 2,4-dimethyl sulfolane should be stored in a cool, dry, well-ventilated place, away from open flames and high temperatures.
Use:
1. Solvent: 2,4-Dimethyl Sulfolane is a polar solvent that can be used to dissolve organic and inorganic substances.
2. reaction intermediate: 2,4-dimethyl sulfolane can be used as a reaction intermediate in the process of organic synthesis, commonly used in the synthesis of catalysts or promoters.
3. Drug synthesis: 2,4-Dimethylsulfolane is widely used in the field of drug synthesis, such as the synthesis of antibiotics, hormones and other drugs.
Preparation Method:
The preparation methods of 2,4-dimethyl sulfolane are mainly as follows:
1. sulfuric acid method: methyl cyclobutane is oxidized to generate 2,4-dimethyl cyclobutanone, and then reacted with sulfuric acid to generate 2,4-dimethyl sulfolane.
2. ammonium chloride method: the reaction of methyl cyclobutene and ammonium chloride to generate 2-methyl cyclobutanone, and then react with sodium bisulfite to generate 2,4-dimethyl sulfolane.
Safety Information:
1. 2,4-Dimethyl sulfolane is irritating and may cause irritation and burns when in contact with skin and eyes. Direct contact should be avoided.
2. in use or operation, should wear appropriate protective gloves, glasses and protective clothing.
3. If inhaled or ingested by mistake, seek medical attention immediately.
Last Update：2024-04-09 02:00:40
